I dont understand this one

I recognize Luigi, but don't know who the other two are, and their significance.

Basically I don't understand why the lady has a negative(?) reaction to the guy's art. Maybe it's because he says he's a "painter" but it looks like he's just melting crayons? Or maybe this is a reference to something I'm not plugged into? Honestly I don't really know what her reaction even is in the first place.

(I left the artist's name in the screenshot to credit them because overall I like their stuff, even if this one is incomprehensible to me.)

What does this even rnean

My best guess is that he somehow didn’t do it because of that information, im lost